Scott Bakula, as Quintin Mills, 1983
Marcia Cross, as Tanya, Cass's date, March 21 and 24, 1986
Kristin Davis, as Page, November 29-30, 1990
Gil Gerard, as Fred Warner, January 14, 1972. He was seen at the top of the scene exiting the law office. His one line: "Thank you, Mr. Randolph, Mr. Curtin."
Thomas Gibson, as Sam Fowler, temporary replacement, May 15 - June 19, 1990
Kelsey Grammer, as (1) a head paramedic, 1982, and (2) Dr. Canard, recurring, 1984
Michael Gross, as Randy, several eisodes, July 1981
Melissa Joan Hart, as a roller-bladder, one episode, 1986
Eriq LaSalle, as Julie Ann's date, 1987
Matt Lauer, as a gallery patron, one episode, 1982
Lindsay Lohan, as Alli Fowler, 19 episodes, 1996-1997
Wendie Malick, as Cecile's henchwoman, May 6, 1986
Marla Maples, as Jason's date, one episode, 1988
John C. McGinley, as Ned, 1985-1986
Chris Noth, as (1) Jimmy, 1985, and (2) a dean, 1988
Ed O'Neill, as Lenny, 1981
Luke Perry, as Kenny, Josie's manager and one of the two Frame borders, recurring, 1988-1989
Brad Pitt, as Chris, a high school student in a location shot with Michael and John, two episodes, May 1987
Ving Rhames, as Czaja Carnek, recurring, 1986
Janine Turner, as Patricia Kirkland, an old girlfriend of Scott's, recurring, 1986-1987
Billy Dee Williams, as the Assistant D.A., recurring, 1967
Henry Winkler, as an intern, June 20, 1972